INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR Russian patent published in 2021 - IPC C07D409/04 C07D409/06 C07D409/14 C07D417/06 C07D417/10 C07D495/04 A61K31/405 A61K31/4365 A61K31/4439 A61P11/06 A61P37/08 A61P43/00 

Abstract RU 2756270 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to indole compounds of the formula (I), in which the values of A, L, T, R3-R5 are disclosed in the claims, and its pharmaceutically acceptable salts. The compounds can be used as CRTH2 inhibitor. The invention also relates to the use of compounds of the formula (I) for the treatment of a disease related to CRTH2 receptor, for example, asthma or allergic rhinitis.

EFFECT: obtaining compounds for the treatment of diseases related to CRTH2 receptor.

14 cl, 1 tbl, 82 ex

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RU 2 756 270 C2

Authors

Yao Yuanshan

Chen Bin

Chen Yuan

Li Ao

Syuj Zhan

Khuan Chzhenshen

Tian Dundun

Li Khunvej

Yan Chenshuaj

Li Tszyan

Chen Shukhuej

Dates

2021-09-29Published

2017-07-21Filed