5T4 AND 4-1BB ANTIGEN-BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS Russian patent published in 2023 - IPC C07K16/28 C07K16/30 A61K39/395 A61P35/00 

Abstract RU 2804458 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to a bispecific polypeptide for use in the treatment of a disorder associated with the expression of 5T4. Also a method of treating cancer in a subject with the help of the said antibody is disclosed.

EFFECT: invention makes it possible to effectively treat cancer characterized by 5T4 expression.

20 cl, 40 dwg, 23 ex, 33 tbl

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RU 2 804 458 C2

Authors

Benvenyu, Devid

Ernandes-Ojos, Gabriela

Misher, Linda

Mitchell, Daniel

Fritsell, Sara

Varas, Laura

Ellmark, Peter

Zall, Anna

Fyurebring, Kristina

Fon Shants, Laura

Dates

2023-10-02Published

2018-07-20Filed