UNITY STRAIN OF THE CANINE MASTADENOVIRUS A VIRUS OF SEROTYPE 2 CANINE ADENOVIRUS FOR THE MANUFACTURE OF BIOLOGICAL PRODUCTS FOR THE DIAGNOSTICS AND SPECIFIC PREVENTION OF SEROTYPE 2 CANINE ADENOVIRUS Russian patent published in 2023 - IPC C12N7/00 C12R1/93 

Abstract RU 2804636 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a new Unity strain of serotype 2 canine adenovirus, of Adenoviridae family, Mastadenovirus genus, Canine mastadenovirus A species, serotype 2 deposited in the collection of strains of microorganisms of FGBU "ARRIAH" under registration number No. 456 - dep/23-6 — GKSHM FGBI "ARRIAH". The presented strain is reproduced in transplanted cell culture of the Madin-Darby Canine Kidney (MDCK). In a transplanted cell culture of MDCK, within 72 hours of incubation, the titer of infectious activity of the virus reaches 3.75±0.25 lg TCD50/cm3, maintaining the original characteristics when passaged in cell culture for 5 passages.

EFFECT: presented strain can be used for the manufacture of biological products for the diagnostics and specific prevention of serotype 2 canine adenovirus and for the control of the antigenic activity of vaccines against this disease.

1 cl, 3 dwg, 4 tbl, 6 ex

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RU 2 804 636 C1

Authors

Galkina Tatyana Sergeevna

Klimova Anastasiya Antonovna

Komarova Anna Aleksandrovna

Doronin Maksim Igorevich

Dates

2023-10-03Published

2023-05-02Filed