FIELD: biotechnology.
SUBTANCE: invention relates to the field of biotechnology. A group of inventions is described, including the use of a compound carrying a glycomodified Fc fragment as an immunosuppression inhibitor in the treatment of cancer-associated immunosuppression and a pharmaceutical composition for the treatment of cancer-associated immunosuppression containing an effective amount of (i) a compound carrying a glycomodified Fc fragment and an effective amount of (ii) an inhibitor protein inhibitor immune checkpoint. In one embodiment, a compound carrying a glycomodified Fc fragment is a glycomodified antibody.
EFFECT: invention expands the arsenal of drugs for the treatment of immunosuppression associated with cancer.
13 cl, 45 dwg, 18 tbl, 9 ex
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