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(19)

(11)

2 763 298

(13)

(51)

IPC

C07K14/54(2006-01-01)

C07K14/715(2006-01-01)

C07K19/00(2006-01-01)

C07K16/28(2006-01-01)

C12P21/02(2006-01-01)

A61K38/20(2006-01-01)

A61K39/395(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2017144606, 2012-06-22

(24)

Start date

2012-06-22

(22)

Actual filing date

2012-06-22

(45)

Published

2021-12-28

(72)

Inventor

Morisso Sebastyan DanelTeppa ZheraldinZhak Yannik Loran ZhozefRober Bruno Zhilber MarkDe Martinoff Gi Lyuk MishelBeshar David

(73)

Holder

Cytune PharmaInserm National De La Sante Et De La Recherche Medicale)

IMMUNOCYTOKINES BASED ON IL-15 AND IL-15Rα OF THE SUSHI DOMAIN Russian patent published in 2021 - IPC C07K14/54 C07K14/715 C07K19/00 C07K16/28 C12P21/02 A61K38/20 A61K39/395 A61P35/00

Abstract RU 2763298 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, specifically to interleukin-15 (IL-15) conjugates, and can be used in medicine for treating cancer. A conjugate of IL-15 and IL-15Rα of the sushi domain is obtained.

EFFECT: invention ensures production of IL-15 agonists with a high yield in CHO cells.

8 cl, 12 dwg

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RU 2 763 298 C2

Authors

Morisso Sebastyan Danel

Teppa Zheraldin

Zhak Yannik Loran Zhozef

Rober Bruno Zhilber Mark

De Martinoff Gi Lyuk Mishel

Beshar David

Dates

2021-12-28—Published

2012-06-22—Filed