IMMUNOCYTOKINES BASED ON IL-15 AND IL-15Rα OF THE SUSHI DOMAIN Russian patent published in 2021 - IPC C07K14/54 C07K14/715 C07K19/00 C07K16/28 C12P21/02 A61K38/20 A61K39/395 A61P35/00 

Abstract RU 2763298 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, specifically to interleukin-15 (IL-15) conjugates, and can be used in medicine for treating cancer. A conjugate of IL-15 and IL-15Rα of the sushi domain is obtained.

EFFECT: invention ensures production of IL-15 agonists with a high yield in CHO cells.

8 cl, 12 dwg

Similar patents RU2763298C2

Title Year Author Number
USE OF THE ANTI-O-ACETYLATED GANGLIOSIDE GD2 ANTIBODY FOR IMPROVING THE THERAPEUTIC POTENTIAL OF DRUGS 2017
  • Birkl, Stefan
  • Flerans, Zhyulen
  • Farazh, Sebastyan
  • Le Dussal, Zhan-Mark
  • Koshonno, Deni
  • Term, Mikael
  • Assulin, Brizhitt
RU2771173C2
IL-17A-BINDING POLYPEPTIDES 2016
  • Frreid Fredrik
  • Feldwisch Jcachim
  • Klint Susanne
  • Gudmudsdotter Lindvi
RU2749712C2
ANTIBODIES DIRECTED AGAINST THE INTERLEUKIN 36 (IL-36R) RECEPTOR 2016
  • Bauerz, Piter
  • Maknajt, Endryu Dzhon
  • King, Devid Dzh.
  • Londi, Marko
RU2745898C2
IL-10/FC FUSION PROTEINS SUITABLE AS IMMUNOTHERAPY ENHANCERS 2020
  • Go, Yujgan
  • Tan, Li
  • Se, Yuj-Tsin
RU2825306C1
DOG ANTIBODIES WITH MODIFIED CH-CH SEQUENCES 2014
  • Morsey, Mohamad
  • Zhang, Yuanzheng
  • Tarpey, Ian
RU2815059C2
DOG ANTIBODIES WITH MODIFIED CH2-CH3 SEQUENCES 2014
  • Morsey, Mohamad
  • Zhang, Yuanzheng
  • Tarpey, Ian
RU2801209C2
ANTI-IL-5 ANTIBODIES 2017
  • Liddament, Mark Terens
  • Dojl, Entoni
  • Klark, Adam
  • Lejn, Devid Khose Sajmon
  • Kuksi, Bridzhit Enn
RU2758008C2
STABLE COMPOSITIONS OF ANTI-TIGIT ANTIBODIES, INDIVIDUALLY AND IN COMBINATION WITH ANTIBODIES AGAINST PROGRAMMED DEATH RECEPTOR 1 (PD-1), AND METHODS OF THEIR USE 2018
  • De, Arnab
  • Narasimkhan, Chakravarti Nachu
RU2820576C2
PEPTIDES AND THEIR USE IN TREATMENT OF DISEASES, DISORDERS OR CONDITIONS ASSOCIATED WITH MUTANT p53 2017
  • Rotter, Varda
  • Oren, Moshe
  • Tal, Perry
  • Eizenberger, Shay
  • Ben-Shimon, Avi
RU2762089C2
MULTIMERIZING POLYPEPTIDES DERIVED FROM DOMAIN WITH ROLL-TYPE PENTONE BASE OF ADENOVIRUS 2019
  • Garzoni Frederic
RU2820522C2

RU 2 763 298 C2

Authors

Morisso Sebastyan Danel

Teppa Zheraldin

Zhak Yannik Loran Zhozef

Rober Bruno Zhilber Mark

De Martinoff Gi Lyuk Mishel

Beshar David

Dates

2021-12-28Published

2012-06-22Filed