FIELD: medicine; laboratory diagnostics; obstetrics; neonatology and pediatrics.
SUBSTANCE: invention can be used to assess morphofunctional disorders of the placenta in myco- and ureaplasma infections. In samples of unfixed placenta, the genome of mycoplasmas Mycoplasma hominis and ureaplasmas Ureaplasma urealyticum and Ureaplasma parvum is determined by PCR, excluding other perinatally significant infections in the first hours after birth. Morphometry of the terminal villi of the placenta is carried out in 5 fields of view with determination of the area, vertical, horizontal dimensions and perimeter. At titer ≥104 GE/ml myco-/ureaplasma infections and a decrease in area indicators to 1,830.4±116.8 µm2, vertical 47.18±1.54 µm, horizontal 52.46±1.72 microns in size and perimeter 167.04±5.46 µm of terminal villi morphofunctional disorders of the placenta are assessed.
EFFECT: method provides increased objectivity and accuracy in diagnosing morphofunctional disorders of the placenta during myco- and ureaplasma infections due to a comprehensive assessment of morphofunctional changes in the placenta, taking into account its infection with opportunistic pathogens.
1 cl, 2 dwg, 1 tbl, 2 ex
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