FIELD: medicine; therapy.
SUBSTANCE: group of inventions is intended for treatment of diseases such as neurodegenerative disorders. New derivatives of the compound of formula (I), its pharmaceutically acceptable isomers, racemates or salts are presented. In another embodiment, a pharmaceutical composition containing the said compounds is provided.
EFFECT: group of inventions provides new derivatives of compounds of formula (I), its pharmaceutically acceptable isomers, racemates or salts, as well as a pharmaceutical composition containing these compounds, which are used as thyroid hormones for the treatment of neurodegenerative diseases such as acute disseminated encephalomyelitis, acute hemorrhagic leukoencephalitis, Refsum's disease in adults, infantile Refsum's disease, Alexander's disease, Alzheimer's disease, Balo's concentric sclerosis, Canavan's disease, central pontine myelinolysis, cerebral palsy, cerebrotendinous xanthomatosis, chronic inflammatory demyelinating polyneuropathy, Devic's syndrome, diffuse myelinoclastic sclerosis, encephalomyelitis, Guillain's syndrome Barre, idiopathic inflammatory demyelinating disease, Krabbe disease, Leber hereditary optic neuropathy, Marburg multiple sclerosis, multiple sclerosis, Marchiafava-Bignami disease, metachromatic leukodystrophy, leukodystrophy, multifocal motor neuropathy, paraproteinemic demyelinating polyneuropathy, Pelizaeus-Merzbacher disease, peroneal myoatrophy , progressive multifocal leukoencephalopathy, transverse myelitis, tropical spastic paraparesis, van der Knaap disease, X-linked adrenoleukodystrophy or Zellweger syndrome.
14 cl, 2 tbl, 60 ex
(I)
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