FIELD: electroanalytical chemistry.
SUBSTANCE: chiral voltammetric sensor for selective recognition and determination of enantiomers of naproxen, made of glassy carbon with an applied composite modifier consisting of a mixture of the polyelectrolyte complex chitosan-chitosan succinamide and chelate complexes of the general structure [Me(Ln)x(Ln')y] or [Me(Ln)x(Ln')y(H2O)z], where Me is a Cu(II) or Zn(II) ion; Ln and Ln' are enantiomers of α-amino acids, non-electroactive in the accessible potential range, taken in the ratio of 0.002-0.02 g of chelate complex per 2 ml of 0.005% solution of the chitosan-chitosan succinamide polyelectrolyte complex.
EFFECT: ability to determine the content of individual enantiomers of the optically active substance of the drug Naproxen in aqueous solutions, urine and blood plasma using an electroanalytical method.
1 cl, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ENANTIOSELECTIVE COMPOSITE VOLTAMMETRIC SENSOR BASED ON COMBINATION OF AlPO-11 ALUMINOPHOSPHATE ZEOLITE AND BETULINIC ACID | 2023 |
|
RU2814614C1 |
| VOLTAMMETRIC SENSOR FOR RECOGNITION AND DETERMINATION OF TYROSINE ENANTIOMERS | 2024 |
|
RU2820023C1 |
| PREPARATION, POSSESSING GASTROPROTECTIVE ACTIVITY | 2014 |
|
RU2536225C1 |
| METHOD FOR ASYMMETRIC ALKYNYLATION OF ALPHA-IMINOESTERS | 2006 |
|
RU2434847C2 |
| METHOD OF PRODUCING (S)-7,8-DIFLUORO-2,3-DIHYDRO-3-METHYL-4H-[1,4]BENZOXAZINE | 2010 |
|
RU2434004C1 |
| METHOD FOR SEPARATION OF RACEMIC 3-(2-METHOXYPHENOXY)-1,2- PROPANEDIOL AND 3-(2-METHYLPHENOXY)-1,2-PROPANEDIOL FOR ENANTIOMERS | 2002 |
|
RU2213724C1 |
| METHOD OF SYNTHESIS OF α-ARYLPROPIONIC ACIDS | 1990 |
|
RU2086532C1 |
| METHOD OF OBTAINING CHIRAL PLANAR PLATE FOR THIN LAYER CHROMATOGRAPHY OF OPTICAL ISOMERS | 2012 |
|
RU2545315C2 |
| CATALYST OF ASYMMETRICAL HYDROGENATION OF DEHYDROAMINO ACID AND THE METHOD OF ITS PRODUCTION | 2016 |
|
RU2621727C1 |
| METHOD OF PRODUCING (S)-3-AMINOMETHYL-5-METHYLHEXANOIC ACID | 2015 |
|
RU2643373C2 |
