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2 799 639

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IPC

C07D487/22(2006-01-01)

A61K31/4985(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2022134693, 2022-12-28

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Start date

2022-12-28

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Actual filing date

2022-12-28

(45)

Published

2023-07-07

(72)

Inventor

Baibakova Olga VladimirovnaEremina Valeriia ValerevnaKulagina Daria AleksandrovnaAlekseeva Natalia AlekseevnaSysoliatin Sergei Viktorovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Problem Khimiko-Energeticheskikh Tekhnologij Sibirskogo Otdeleniya Rossijskoj Akademii Nauk So Ran)

4-(3,4-DIBROMOTHIOPHENECARBONYL)-10-ISONICOTINYL-2,6,8,12-TETRAACETYL-2,4,6,8,10,12-HEXAAZATETRA-CYCLO[5,5,0,0,0]DODECANE AS AN ANALGESIC AND A METHOD OF ITS OBTAINING Russian patent published in 2023 - IPC C07D487/22 A61K31/4985 A61P29/00

Abstract RU 2799639 C1

FIELD: organic chemistry.

SUBSTANCE: group of inventions includes 4-(3,4-dibromothiophenecarbonyl)-10-isonicotinyl-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetra-cyclo[5,5,0,0^3.11,0^5.9] dodecane of formula (I) and the method of its preparation. The method is carried out by acylation of 4-(3,4-dibromothiophenecarbonyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetra-cyclo[5,5,0,0^3.11,0^5.9] dodecane isonicotinic acid chloride.

EFFECT: 4-(3,4-dibromothiophenecarbonyl)-10-isonicotinyl-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetra-cyclo[5,5,0,0^3,11,0^5,9] dodecane with analgesic activity.

2 cl, 1 tbl, 2 ex

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RU 2 799 639 C1

Authors

Baibakova Olga Vladimirovna

Eremina Valeriia Valerevna

Kulagina Daria Aleksandrovna

Alekseeva Natalia Alekseevna

Sysoliatin Sergei Viktorovich

Dates

2023-07-07—Published

2022-12-28—Filed