4,10-DI(ETHOXYACETYL)-2,6,8,12-TETRAACETYL-2,4,6,8,10,12-HEXAAZATETRACYCLO[5,5,0,0,0] DODECANE AS AN ANALGESIC AGENT AND A METHOD FOR PRODUCTION THEREOF Russian patent published in 2020 - IPC C07D487/22 A61K31/4985 A61P29/00 

Abstract RU 2736936 C1

FIELD: chemistry.

SUBSTANCE: invention relates to compound - 4,10-di(2-ethoxyacetyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,03,11,05,9]dodecane. Invention also relates to a method for its preparation, which includes acylation of 2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,03,11,05,9]dodecane with 2-ethoxyacetic acid chloride.

EFFECT: obtaining a novel compound of formula (I), having analgesic activity, which can be used in medicine.

2 cl, 4 tbl, 2 ex

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Authors

Krylova Svetlana Gennadevna

Poveteva Tatyana Nikolaevna

Suslov Nikolaj Innokentevich

Zueva Elena Petrovna

Nesterova Yuliya Vladimirovna

Afanaseva Olga Gennadevna

Kulpin Pavel Valerevich

Amosova Evdokiya Naumovna

Razina Tatyana Georgievna

Rybalkina Olga Yurevna

Safonova Elena Andreevna

Zhdanov Vadim Vadimovich

Kalashnikov Aleksandr Ivanovich

Bajbakova Olga Vladimirovna

Bakholdina Lyubov Alekseevna

Eremina Valeriya Valerevna

Sonina Ekaterina Georgievna

Kulagina Darya Aleksandrovna

Sysolyatin Sergej Viktorovich

Dates

2020-11-23Published

2020-06-25Filed