4,10-BIS((±)-5-BENZOYL-2,3-DIHYDRO-1H-PYRROLO[1,2-A]PYRROLE-1-CARBONYL)-2,6,8,12-TETRAACETYL-2,4,6,8,10,12-HEXAAZATETRACYCLO[5,5,0,0,0]DODECANE AS ANALGETIC MEANS AND METHOD OF ITS OBTAINING Russian patent published in 2015 - IPC C07D487/22 A61K31/4188 A61K31/4985 A61P29/00 

Abstract RU 2558148 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a novel chemical substance - 4,10-bis((±)-5-benzoyl-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carbonyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,03,11,05,9]dodecane The invention also relates to a method of its obtaining, which consists in the acylation of 2,6,8,12-tetraacetyl-2,4,6,8,10,12- hexaazatetracyclo [5,5,0,03,11,05,9]dodecane by chloranhydride 5-benzoyl-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid.

EFFECT: novel compound, which has analgetic activity, is obtained.

2 cl, 1 tbl, 2 ex

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RU 2 558 148 C1

Authors

Krylova Svetlana Gennad'Evna

Amosova Evdokija Naumovna

Zueva Elena Petrovna

Razina Tat'Jana Georgievna

Rybalkina Ol'Ga Jur'Evna

Lopatina Ksenija Aleksandrovna

Sysoljatin Sergej Viktorovich

Kalashnikov Aleksandr Ivanovich

Malykhin Valerij Viktorovich

Dygaj Aleksandr Mikhajlovich

Zhdanov Vadim Vadimovich

Dates

2015-07-27Published

2014-07-09Filed