USE OF 2-METHYL-4-[7-(TRIFLUOROMETHYL)PHENYL]-1,2,4,5-TETRAHYDRO-3H-PYRROLO[1,2-a][1,4]DIAZEPIN-3-ONE AS ANTIFUNGAL AGENT AGAINST YEAST FUNGI Russian patent published in 2023 - IPC A61K31/551 A61P31/10 C07D487/04 

Abstract RU 2809051 C1

FIELD: medicinal chemistry.

SUBSTANCE: invention relates to the use of 2-(4-bromophenyl)-7-ethyl-1,2,4,5-tetrahydro-3H-pyrrolo[1,2-a][1,4]diazepine-3-one of formula 1 as an antifungal agent against the yeast Candida albicans.

EFFECT: obtaining a compound with pronounced antimycotic activity against the yeast fungi Candida albicans, as well as low toxicity.

1 cl, 1 tbl, 3 ex

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RU 2 809 051 C1

Authors

Uchuskin Maksim Grigorevich

Mendogralo Elena Iurevna

Makarov Anton Sergeevich

Nikiforova Elena Aleksandrovna

Rubtsov Aleksandr Evgenevich

Nesterova Larisa Iurevna

Tkachenko Aleksandr Georgievich

Sorotskaia Liudmila Nazarovna

Dates

2023-12-06Published

2023-04-29Filed