FIELD: medicinal chemistry.
SUBSTANCE: invention relates to the use of 2-(4-bromophenyl)-7-ethyl-1,2,4,5-tetrahydro-3H-pyrrolo[1,2-a][1,4]diazepine-3-one of formula 1 as an antifungal agent against the yeast Candida albicans.
EFFECT: obtaining a compound with pronounced antimycotic activity against the yeast fungi Candida albicans, as well as low toxicity.
1 cl, 1 tbl, 3 ex
Title | Year | Author | Number |
---|---|---|---|
USE OF 7-METHYL-2-(4-METHYLPHENYL)-1,2,4,5-TETRAHYDRO-3H-PYRROLO[1,2-a][1,4]DIAZEPIN-3-ONE AS AN ANTIFUNGAL AGENT AGAINST YEAST FUNGI | 2023 |
|
RU2809053C1 |
USE OF 5-(4-METOXYPHENYL)-7-METHYL-1,2,4,5-TETRAHYDRO-3H-PYRROLO[1,2-a][1,4]DIAZEPIN-3-ONE AS AN ANTIFUNGAL AGENT AGAINST YEAST FUNGI | 2023 |
|
RU2810715C1 |
USE OF 7-METHYL-5-[4-(TRIFLUOROMETHYL)PHENYL]-1,2,4,5-TETRAHYDRO-3H-PYRROLO[1,2-a][1,4]DIAZEPIN-3-ONE AS AN ANTIFUNGAL AGENT AGAINST YEAST FUNGI | 2023 |
|
RU2808981C1 |
APPLICATION OF 5-[(1H-INDOL-3-YL)METHYL]-7-METHYL-2,3-DIHYDRO-1H-PYRROLO[1,2-D][1,4]DIAZEPIN-4(5H)-ONE AS AN ANTIFUNGAL AGENT FOR YEASTS | 2023 |
|
RU2803571C1 |
USE OF 1-METHYL-5-(4-CHLOROPHENYL)-4,5-DIHYDRO-6H-PYRROLO[1,2-a][1,4]BENZODIAZEPIN-6-ONE AS AN ANTIFUNGAL AGENT AGAINST YEAST FUNGI | 2023 |
|
RU2809148C1 |
APPLICATION OF 10-METHYL-6,7-DIHYDRO-5H-PYRIDO[2,3-b]-PYRROLO[1,2-d][1,4]DIAZEPINE AS AN ANTIFUNGAL AGENT AGAINST YEASTS | 2023 |
|
RU2803600C1 |
USE OF 1-METHYL-4,5-DIHYDRO-6H-PYRIDO[1,2-a][1,4]BENZODIAZEPINE-6-ONE AS ANTIFUNGAL AGENT AGAINST YEASTS | 2023 |
|
RU2809026C1 |
USE OF 1-METHYL-8,9-DIMETHOXY-4,5-DIHYDRO-6H-PYRROLO[1,2-A][1,4]BENZODIAZEPIN-6-ONE AS AN ANTIFUNGAL AGENT AGAINST YEAST FUNGI | 2023 |
|
RU2808993C1 |
USE OF 4,6-DIMETHYL-1,2-DIHYDROPYRROLO[1,2-a]PYRAZIN-3(4H)-ONE AS AN ANTIFUNGAL AGAINST YEASTS | 2023 |
|
RU2806191C1 |
USE OF 1-ACETYL-2-(2-OXOBUTYL)-6-CHLORINDOLIN-3-ONE AS ANTIFUNGAL AGENT AGAINST YEAST FUNGI | 2023 |
|
RU2809002C1 |
Authors
Dates
2023-12-06—Published
2023-04-29—Filed