FIELD: pharmaceuticals.
SUBSTANCE: invention relates to novel cyclic dinucleotide derivatives (CDNs) with STING agonist activity, antibody-drug conjugates formed by conjugating novel cyclic dinucleotide derivatives and antibodies against target cells to each other via a linker, a pharmaceutical composition containing antibody-drug conjugates, and a method of treating cancer associated with STING agonist activity.
EFFECT: obtaining a new cyclic dinucleotide derivative and its antibody-drug conjugate.
82 cl, 22 dwg, 2 tbl, 127 ex
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