OPHTHALMIC NANOEMULSION COMPOSITION CONTAINING CYCLOSINO AND PREPARATION METHOD THEREOF Russian patent published in 2019 - IPC A61K38/13 A61K47/30 A61K47/44 A61K9/113 A61P27/02 

Abstract RU 2683271 C2

FIELD: pharmaceutical industry.

SUBSTANCE: invention refers to pharmaceutical industry, namely to an ophthalmic nano emulsion composition. An ophthalmic nano emulsion composition having a range of average particle size from 1 nm to 100 nm contains: cyclosporine, castor oil, polyoxyl 35 castor oil, a hydrophobic emulsifier, an aqueous solvent taken in certain amounts. Disclosed are versions of an ophthalmic nano emulsion composition comprising: cyclosporine, castor oil, polyoxyl 35 castor oil, one or more hydrophobic emulsifiers, an aqueous solvent taken in certain amounts.

EFFECT: disclosed combination of a hydrophilic emulsifier and a hydrophobic emulsifier, castor oil in a certain amount exceeding the amount of cyclosporine forms a stable and transparent ophthalmic nano emulsion composition.

8 cl, 3 dwg, 7 ex, 13 tbl

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RU 2 683 271 C2

Authors

Li Dzoon Joub

Shin Joun Dzae

Riu Sang-Rok

Dates

2019-03-27Published

2014-05-20Filed