STABLE AQUEOUS SOLUTION Russian patent published in 2018 - IPC A61K31/427 A61K47/10 A61K47/34 A61K9/08 A61P27/02 

Abstract RU 2665639 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to a liquid ophthalmic preparation comprising (3-{2-[4-isopropyl-2-(4-trifluoromethyl)phenyl-5-thiazolyl]ethyl}-5-methyl-1,2-benzisoxazol-6-yl)oxyacetic acid or a pharmaceutically acceptable salt thereof and tyloxapol or octoxynol, as well as the use tyloxapol and octoxynol for higher stability (3-{2-[4-isopropyl-2-(4-trifluoromethyl)phenyl-5-thiazolyl]ethyl}-5-methyl-1,2-benzisoxazol-6-yl)oxyacetic acid.

EFFECT: invention allows obtaining a liquid ophthalmic composition (3-{2-[4-isopropyl-2-(4-trifluoromethyl)phenyl-5-thiazolyl]ethyl}-5-methyl-1,2-benzisoxazol-6-yl)oxyacetic acid, resistant to light and heat.

24 cl, 4 ex, 12 tbl

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RU 2 665 639 C2

Authors

Sikamura Yuko

Khigasimura Yuka

Dates

2018-09-03Published

2014-01-30Filed