FIELD: biotechnology.
SUBSTANCE: present invention is related in particular to a new fusion peptide containing growth differentiation factor 15 (GDF15) and a polypeptide region capable of O-glycosylation.
EFFECT: invention makes it possible to increase the lifetime of the GDF15 peptide in vivo and can be used in medical practice in the treatment of diseases associated with GDF15 deficiency.
20 cl, 12 tbl, 12 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| FUSION POLYPEPTIDE INCLUDING Fc REGION OF IMMUNOGLOBULIN AND GDF15 | 2020 |
|
RU2797520C2 |
| SPECIFIC TO MUCIN-1 POLYPEPTIDE AND ITS USE | 2021 |
|
RU2805840C1 |
| FUSED SERPINE POLYPEPTIDES AND METHODS OF THEIR APPLICATION | 2015 |
|
RU2746550C2 |
| FUSED SERPIN POLYPEPTIDES AND METHODS FOR USE THEREOF | 2012 |
|
RU2698655C2 |
| FUSED SERPIN POLYPEPTIDES AND METHODS FOR USE THEREOF | 2019 |
|
RU2728861C1 |
| FUSED POLYPEPTIDE WITH ANTI-CANCER ACTIVITY | 2016 |
|
RU2754466C2 |
| POLYPEPTIDES THAT BIND TO THE C5 COMPONENT OR TO SERUM ALBUMIN AND THEIR FUSION PROTEINS | 2018 |
|
RU2794359C2 |
| EXPRESSION OF NITROGENASE POLYPEPTIDES IN PLANT CELLS | 2018 |
|
RU2809244C2 |
| POLYPEPTIDE COMPRISING ANTIGEN-BINDING DOMAIN AND TRANSPORT SEGMENT | 2018 |
|
RU2815452C2 |
| CD37-BINDING MOLECULES AND THEIR IMMUNOCONJUGATES | 2011 |
|
RU2742743C2 |
