FIELD: medicine.
SUBSTANCE: invention relates to a method of treating acute myeloid leukaemia. A method of treating acute myeloid leukaemia in a subject in need thereof comprises administering to the subject an effective amount of 5-fluoro-2-(6-fluoro-2-methyl-1H-benzo[ d ]imidazol-1-yl)-N4-[4-(trifluoromethyl)phenyl]pyrimidine-4,6-diamine, the structure of which is represented by formula (I):
Formula (I)
or a pharmaceutically acceptable salt thereof or a pharmaceutical composition thereof, wherein the effective amount reaches an average plasma concentration over 24 hours of 3 hours*mcg/ml to 70 hours*mcg/ml.
EFFECT: above invention makes it possible to treat acute myeloid leukemia in a subject in need thereof by injecting to the subject an effective amount of a compound represented by formula (I).
10 cl, 6 dwg, 3 ex
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