AQUEOUS COMPOSITION, PARTICULARLY FOR TREATMENT OF MUCOUS MEMBRANE AND/OR WOUNDS Russian patent published in 2024 - IPC A61K9/08 A61K31/53 A61K47/10 A61P17/02 A61P31/00 

FIELD: pharmacology.

SUBSTANCE: aqueous composition in the form of an aqueous solution or hydrogel for the prevention or treatment of infections and/or infectious diseases of the mucous membrane and/or wounds contains a dihydrotriazine derivative, its tautomer or a pharmaceutically acceptable salt, formula:

, R₁ — (i) phenyl or phenylalkyl group, optionally has 1–3 substituents selected from halogen, C_1-6-alkoxy, hydroxy, C_1-6-haloalkyl, C_1-6-alkyl, sulfamide and C_1-6-haloalkoxy groups, (ii) a naphthyl or naphthylalkyl group, (iii) a heterocyclic, heterocyclalkyl or heterocyclaminoalkyl group, (iv) an alkyl group with 1–16 carbon atoms, (v) a cycloalkyl or cycloalkylalkyl group; R₁' is a hydrogen atom that is bonded to the nitrogen atom in position 1 or 3 of the dihydrotriazine ring, R₂ and R₃ are independently a hydrogen atom or a methyl group, R₄ is an alkyl group with 7–16 carbon atoms, the dotted line shows that the position of the double bond may be between positions 1 and 2 or 2 and 3 of the dihydrotriazine ring, and zwitterionic or a combination of nonionic and zwitterionic surfactants.

EFFECT: invention provides effectiveness in terms of bactericidal activity.

14 cl, 15 tbl, 2 ex