METHOD OF STABILIZING PRUSSIAN BLUE NANOPARTICLES AND MANUFACTURING SENSORS BASED ON THEM Russian patent published in 2024 - IPC C01G53/00 C09D5/00 C01G49/00 C01C3/12 B82Y40/00 

FIELD: analytical chemistry; electrochemical methods of analysis; nanotechnology; medical diagnostics; industrial and environmental monitoring.

SUBSTANCE: invention can be used in the manufacture of biosensor systems, as well as catalytic labels and sensor coatings for determining hydrogen peroxide. Nickel hexacyanoferrate is deposited onto the surface of Prussian blue nanoparticles to form a “core-shell” structure using a growth mixture containing 0.3–2.1 mM K₃(Fe(CN)₆] and 0.5–3.5 mM NiCl₂, in a background electrolyte containing 0.5 M KCl and 0.1 M HCl. Precipitation is carried out with continuous stirring in an ultrasonic bath for 20 s and a concentration of Prussian blue nanoparticles of 5–50 nM. The resulting suspensions are centrifuged for 30–60 s at a speed of at least 13,000 rpm. Stabilized Prussian Blue nanoparticles are dispersed and stored as a suspension in 7 mM sodium hexametaphosphate in a supporting electrolyte containing 0.5 M KCl and 0.1 M HCl, which improves their stability in neutral media. 2 mcl of a suspension of the indicated stabilized Prussian blue nanoparticles is applied to the surface of the carbon-containing electrode, kept on the surface of the electrode for 24 hours, after which heat treatment is carried out at 100°C for 1 hour.

EFFECT: extending the service life of the resulting sensor coating of a carbon-containing electrode intended for determining hydrogen peroxide.

2 cl, 5 dwg, 2 ex