FIELD: pharmaceuticals.
SUBSTANCE: invention relates to the method of preparation of a compound of formula (IIA). The method involves introduction of a compound of formula (IA) with 0.6 to 1.0 molar equivalent of cyanuric acid chloride into the reaction to form a compound of formula (IIA). The invention also relates to a method of preparing a compound of formula (IIB) from a compound of formula (IB).
(IIA) 
(IA)
(IIB) 
(IB)
EFFECT: proposed methods make it possible to selectively introduce one chlorine atom into the starting diol compounds with a higher yield and can be used for the preparation of synthetic precursors of benzodiazepine dimeric compounds.
34 cl, 19 dwg, 4 ex
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