METHOD FOR DETERMINING OPTIMAL ENERGY PARAMETERS OF LASER-INDUCED PHOTODYNAMIC THERAPY OF DYSPLASIA AND CERVICAL CANCER Russian patent published in 2024 - IPC A61N5/06 G09B23/28 A61K41/00 A61P35/00 

Abstract RU 2815258 C1

FIELD: medicine; oncology.

SUBSTANCE: invention can be used in laser-induced photodynamic therapy of dysplasia and cervical cancer. Method comprises intravenous introduction of photosensitizer based on chlorine e6 in concentration of 1 mg/kg, then the affected area is exposed to laser radiation with wavelength of 660 nm, spot diameter of 10–15 mm, power density of 0.15 W/cm2, energy density of 200–250 J/cm2. Irradiation is carried out until photosensitiser is more than 70 % colorless throughout the depth of the lesion.

EFFECT: method enables increasing the effectiveness of photodynamic therapy of cervical tumor tissues, minimizing side effects and prevent recurrences of the disease by providing a therapeutic effect throughout the depth of the lesion without superficial thermal damages.

1 cl, 4 dwg, 2 ex

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RU 2 815 258 C1

Authors

Alekseeva Polina Mikhajlovna

Efendiev Kanamat Tembotovich

Saveleva Tatyana Aleksandrovna

Moskalev Arkadij Sergeevich

Gilyadova Aida Vladimirovna

Loshchenov Viktor Borisovich

Dates

2024-03-12Published

2023-02-22Filed