FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and concerns a new strain of foot-and-mouth disease virus Aphtae epizooticae genotype SAT-2/XIV, family Picornaviridae, genus Aphthovirus, deposited in the All-Russian State Collection of Exotic Types of Foot and Mouth Disease Virus and Other Animal Pathogens FGBI "ARRIAH" under registration number No. 489 — dep/23-39 — GKShM FGBU VNIIZZH SAT-2/XIV/2023 strain of SAT-2/XIV genotype of foot-and-mouth disease virus. Presented strain is reproduced in transplantable cell cultures of Siberian ibex kidney (PSGK-30), porcine kidney (IB-RS-2), newborn Syrian hamster kidney (BHK-21). In a transplantable suspension cell culture of the Syrian hamster kidney BHK-21/SUSP/ARRIAH for 11.45±0.37 hours of incubation, concentration of 146S component of SAT-2/XIV/2023 strain of SAT-2/XIV genotype of foot-and-mouth disease has average values of 1.94±0.07 mcg/cm3 (68.66±0.64%), preserving the initial characteristics when passaging in a new transplantable suspension cell line BHK-21/SUSP/ARRIAH.
EFFECT: presented strain "SAT-2/XIV/2023" can be used for making biopreparations for diagnosis and specific prevention of foot-and-mouth disease of SAT-2/XIV genotype and for controlling antigenic activity of foot-and-mouth disease vaccines.
1 cl, 2 dwg, 5 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
RU2808493C1 |
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|
RU2806602C1 |
| CULTURE INACTIVATED EMULSION VACCINE AGAINST FOOT-AND-MOUTH DISEASE OF SAT-2/XIV GENOTYPE FROM SAT-2/XIV/2023 STRAIN | 2024 |
|
RU2824660C1 |
| A/EGYPT/EURO-SA/2022 STRAIN OF APHTAE EPIZOOTICAE FOOT-AND-MOUTH DISEASE VIRUS FOR MANUFACTURE OF BIOPREPARATIONS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF FOOT-AND-MOUTH DISEASE GENOTYPE A/EURO-SA | 2023 |
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RU2817256C1 |
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| SAT-1/KENYA/2017 STRAIN OF APHTAE EPIZOOTICAE FOOT AND MOUTH DISEASE VIRUS FOR THE MANUFACTURE OF BIOLOGICAL PRODUCTS FOR THE DIAGNOSTICS AND SPECIFIC PREVENTION OF FOOT AND MOUTH DISEASE VIRUS OF SAT-1/NWZ GENOTYPE | 2023 |
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| APHTAE EPIZOOTICAE FOOT-AND-MOUTH DISEASE VIRUS STRAIN "O NO 2222/TAIWAN/1/2012" FOR PRODUCTION OF BIOPREPARATIONS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF FOOT-AND-MOUTH DISEASE | 2023 |
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RU2807038C1 |
