STRAIN "SAT-2/NORTH AFRICAN/2012" OF APHTAE EPIZOOTICAE FOOT-AND-MOUTH DISEASE VIRUS OF GENOTYPE SAT-2/VII/GHB-12 FOR PRODUCTION OF BIOPREPARATIONS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF FOOT-AND-MOUTH DISEASE Russian patent published in 2024 - IPC C12N7/00 

Abstract RU 2826730 C1

FIELD: biotechnology.

SUBSTANCE: presented strain is reproduced in transplantable cell cultures of Siberian ibex kidney (PSGK-30), pig kidney (IB-RS-2), kidney of a newborn Syrian hamster (BHK-21). In a transplantable suspension cell culture of the kidney of the Syrian hamster BHK-21/SUSP/ARRIAH for 13.95±1.40 hours of incubation concentration of 146S component of the strain "SAT-2/North African/2012" of the genotype SAT-2/VII/Ghb-12 of the foot-and-mouth disease virus has average values 1.36±0.08 mcg/cm3 (65.21±0.22%), preserving the initial characteristics when passaging in the new transplantable suspension cell line BHK-21/SUSP/ARRIAH.

EFFECT: presented strain "SAT-2/North African/2012" can be used for production of biopreparations for diagnosis and specific prevention of foot-and-mouth disease of genotype SAT-2/VII/Ghb-12 and for control of antigenic activity of foot-and-mouth disease vaccines.

1 cl, 2 dwg, 5 tbl, 7 ex

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RU 2 826 730 C1

Authors

Doronin Maksim Igorevich

Mikhalishin Dmitrii Valerevich

Borisov Aleksei Valerevich

Budina Olesia Olegovna

Kharitonova Anastasiia Aleksandrovna

Silanteva Ekaterina Andreevna

Negazina Nadezhda Nikolaevna

Nikiforov Viktor Viktorovich

Dates

2024-09-16Published

2024-06-21Filed