BISPECIFIC ANTIBODIES Russian patent published in 2024 - IPC C07K16/28 C07K16/36 C07K16/46 A61K39/395 A61P7/04 

Abstract RU 2818588 C2

FIELD: biotechnology.

SUBSTANCE: disclosed is a bispecific antibody containing a first antigen-binding site capable of binding factor VII (a), and a second antigen-binding site capable of binding TLT-1. Also disclosed is a pharmaceutical composition containing said antibodies, which is used in the treatment of coagulopathy.

EFFECT: invention enables to obtain bispecific antibodies with improved pharmaceutical properties.

11 cl, 37 tbl, 32 ex

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RU 2 818 588 C2

Authors

Gandi, Prafull, S.

Brejnkholt, Jens

Estergaard, Khenrik

Dates

2024-05-03Published

2020-04-15Filed