FIELD: biotechnology.
SUBSTANCE: disclosed is a bispecific antibody containing a first antigen-binding site capable of binding factor VII (a), and a second antigen-binding site capable of binding TLT-1. Also disclosed is a pharmaceutical composition containing said antibodies, which is used in the treatment of coagulopathy.
EFFECT: invention enables to obtain bispecific antibodies with improved pharmaceutical properties.
11 cl, 37 tbl, 32 ex
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Authors
Dates
2024-05-03—Published
2020-04-15—Filed