FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology. Variants of the method of activation of T-cells of a patient with cancer are proposed. The indicated patient is injected with antibodies against PD-L1 and antibodies against PVRIG, while a subset of the indicated T cells of the patient is activated.
EFFECT: invention can be used in cancer immunotherapy.
24 cl, 333 dwg, 7 tbl, 29 ex
Title | Year | Author | Number |
---|---|---|---|
ANTI-PVRIG ANTIBODIES AND METHODS OF USING | 2016 |
|
RU2732042C2 |
ANTIBODIES AGAINST CXCR2 AND THEIR USE | 2019 |
|
RU2807067C2 |
BISPECIFIC ANTIGEN-BINDING CONSTRUCTS AGAINST HER2 | 2014 |
|
RU2737882C2 |
HYBRID PROTEINS OF sPD-1-Fc VARIANT | 2019 |
|
RU2785993C2 |
IL-12 HETERODIMERIC FC FUSION PROTEINS | 2019 |
|
RU2819097C2 |
ANTIBODIES AGAINST PD-L1 AND THEIR OPTIONS | 2017 |
|
RU2770590C2 |
NEW CRISPR ENZYMES AND SYSTEMS | 2016 |
|
RU2771826C2 |
NEW ENZYMES AND CRISPR SYSTEMS | 2016 |
|
RU2777988C2 |
BISPECIFIC ANTIGEN-BINDING POLYPEPTIDES | 2015 |
|
RU2723940C2 |
INTRODUCTION OF CONSTRUCTED T CELLS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM CANCER | 2017 |
|
RU2757308C2 |
Authors
Dates
2024-10-03—Published
2016-02-19—Filed