METHOD FOR PREDICTION OF RESPONSE TO THERAPY WITH MULTIPLE SCLEROSIS DISEASE MODIFYING DRUGS OF THE FIRST LINE Russian patent published in 2024 - IPC A61B10/00 

Abstract RU 2818847 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to neurology, and can be used to assess probability of formation in patient with multiple sclerosis of optimal response to pathogenetic therapy with multiple sclerosis disease modifying drugs (DMT) of first line. Completeness of recovery after the first exacerbation and the level of disability are assessed by EDSS in points. Using the derived values, the probability of developing the optimal response to the first-line disease modifying therapy (F) is determined. And at value F ≥ 0.5, a high probability of the optimal response to the first-line disease modifying therapy is predicted.

EFFECT: method enables to determine the patients for whom it is reasonable to consider starting the therapy of multiple sclerosis with second-line preparations or earlier switching to second-line DMT taking into account individual indications and contraindications by assessing the aggregate of the most significant indicators.

1 cl, 3 dwg, 2 ex

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RU 2 818 847 C1

Authors

Titova Marina Andreevna

Kamenskikh Ekaterina Mikhailovna

Pashkovskaia Daria Vitalevna

Sirotina Alina Sergeevna

Alifirova Valentina Mikhailovna

Dates

2024-05-06Published

2023-12-01Filed