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RU

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2 819 611

(13)

C1

(51)

IPC

A61K31/37(2006-01-01)

C07D311/16(2006-01-01)

A61P1/00(2006-01-01)

A61P3/10(2006-01-01)

A61P9/00(2006-01-01)

A61P19/00(2006-01-01)

A61P25/00(2006-01-01)

A61P27/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2022135508, 2022-12-31

(24)

Start date

2022-12-31

(22)

Actual filing date

2022-12-31

(45)

Published

2024-05-21

(72)

Inventor

Krasnov Vladimir SergeevichKirsanov Roman SergeevichKhajlova Lyudmila SamuilovnaPopova Lyudmila BorisovnaNazarov Pavel AleksandrovichLyamzaev Konstantin GennadevichFirsov Aleksandr MikhajlovichKorshunova Galina AnatolevnaKotova Elena AvramovnaAntonenko Yurij Nikolaevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Universitet Imeni M.V.Lomonosova"

7-HYDROXYCOUMARIN DERIVATIVE FOR INDUCING MITOPHAGY IN CELLS, METHOD FOR PRODUCTION AND USE THEREOF Russian patent published in 2024 - IPC A61K31/37 C07D311/16 A61P1/00 A61P3/10 A61P9/00 A61P19/00 A61P25/00 A61P27/00 A61P35/00 

Abstract RU 2819611 C1

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention refers to pharmacology and medicine, namely to use of 7-hydroxycoumarin derivative of general formula (I), having protonophore activity. R in formula (I) is a linear alkyl containing 6–15 carbon atoms.

EFFECT: stimulation of selective degradation of mitochondria in cells (mitophagy) by means of 7-hydroxycoumarin derivative of general formula (I).

3 cl, 5 dwg

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RU 2 819 611 C1

Authors

Krasnov Vladimir Sergeevich

Kirsanov Roman Sergeevich

Khajlova Lyudmila Samuilovna

Popova Lyudmila Borisovna

Nazarov Pavel Aleksandrovich

Lyamzaev Konstantin Gennadevich

Firsov Aleksandr Mikhajlovich

Korshunova Galina Anatolevna

Kotova Elena Avramovna

Antonenko Yurij Nikolaevich

Dates

2024-05-21—Published

2022-12-31—Filed

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