METHOD OF TREATING MACULAR RUPTURE COMPLICATED BY DRUSENOID DETACHMENT OF RETINAL PIGMENT EPITHELIUM Russian patent published in 2024 - IPC A61F9/07 A61F9/08 A61K35/19 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to ophthalmology. First stage involves laser coagulation of the retina along the edge of the macular rupture with the following energy parameters: wavelength is 577 nm, power is 50 mWt, pulse duration is 0.03–0.05 s, coagulate diameter is 100 mcm, distance between coagulates is 100 mcm, number of coagulates is from 10 to 12. Then, not less than 2 weeks, but not more than 2 months, the state of the macular zone is assessed using optical coherence tomography and with a decrease in the height of pigment epithelium detachment by 50 % and more from the initial values in the macular zone, the second stage of treatment is carried out. Specifically, transconjunctival three-port 27G vitrectomy is performed through a flat portion of the ciliary body in the presence of an irrigation balanced salt solution (BSS), with removal of posterior hyaloid membrane, adjacent posterior layers of vitreous body, epiretinal membrane and internal border membrane around foveola within vascular arcades. Then maculorexis is performed, starting at the point of the weakest adhesion of the membrane with the underlying layer of the retinal neuroepithelium, moving in a circle by grasping the already separated membrane with tweezers, edges of macular rupture are brought closer to the centre until their complete contact is complicated by drusenoid detachment of retinal pigment epithelium. That is followed by application of autologous conditioned plasma for up to 1 min in volume of 0.1 ml within the vascular arcades; the operation is completed by replacing the balanced salt solution with air. Ports are removed, the sclerostomas are closed, and the patient is placed face down for 8 hours after the operation.

EFFECT: method enables to eliminate metamorphopsia, improve and stabilize visual functions, retinal light sensitivity, restore macular region retina architectonics, when using combined treatment, namely a combination of laser coagulation of retina and surgical treatment of macular rupture.

1 cl, 2 ex