FIELD: chemistry.
SUBSTANCE: application describes a composition comprising (i) a formulation of a therapeutically active agent based on nano- or microparticles, which is suspended in a liquid phase, and (ii) at least one cryoprotective additive selected from C3-C5 alkanes substituted with one or two hydroxyl groups, which stabilizes the particle-containing composition.
EFFECT: cryoprotective agents for particle-containing formulations are disclosed.
5 cl, 5 dwg, 19 tbl, 6 ex
Authors
Dates
2024-06-07—Published
2019-04-25—Filed