METHODS OF DIAGNOSING STROKE, EFFECTIVENESS OF THERAPY, AND DETERMINING RISK OF STROKE Russian patent published in 2024 - IPC G01N33/50 G01N33/68 G01N33/96 C12Q1/6883 

Abstract RU 2821748 C2

FIELD: medicine; clinical diagnostics.

SUBSTANCE: diagnostic method and a method of determining an individual's risk of developing stroke are proposed, including measuring the expression levels of at least three biomarkers selected from the group consisting of PTGS2, HMOX1, LDLR, HSPA1B, G0S2, BAG3, TM4SF1, DUSP1 and ADM. A method is proposed for determining whether an individual who has suffered a stroke has responded to therapy, including measuring the expression levels of at least two biomarkers selected from the group consisting of PTGS2, HMOX1, LDLR, HSPA1B, G0S2, BAG3, TM4SF1, DUSP1 and ADM.

EFFECT: characterization of patients with ischemic stroke and the development of accompanying biomarkers required for assessing the effectiveness of neuroprotective drugs in patients by identifying a common coding signature for the brain affected by ischemic damage in a sample taken from an individual.

21 cl, 4 dwg, 4 tbl, 2 ex

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RU 2 821 748 C2

Authors

Timsit, Serge

Genin, Emmanuelle

Dates

2024-06-26Published

2019-05-16Filed