FIELD: biotechnology.
SUBSTANCE: disclosed is a method for preparing a composition containing secretory IgA and a probiotic, involving: a) providing a source of SIgA in the form of milk, which is not exposed to a temperature higher than 70 °C after expression, or its fraction; b) optionally microfiltration of milk; c) milk pasteurisation at 61–200 °C for 0.1–200 s; d) optional spray drying at temperature of liquid concentrate less than 70 °C; e) mixing with probiotic at 12–45 °C for 10–360 min; and f) optionally spray drying at temperature of liquid concentrate less than 70 °C.
EFFECT: invention widens the range of methods for producing SIgA, having the required level of sterility for baby food, while preserving its bioactivity and ability to enhance the beneficial effect of probiotics after association with them.
9 cl, 10 dwg, 7 tbl, 7 ex
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