NEW HAEMOPHILUS PARASUIS VACCINE Russian patent published in 2024 - IPC C07K14/05 A61K39/102 

FIELD: biotechnology; veterinary science.

SUBSTANCE: disclosed is a protein having at least 69% sequence identity with a protein according to SEQ ID No: 1, or an immunogenic fragment of said protein for use in a preventive method for protecting a pig from infection with Haemophilus parasuis serotype 4 and Haemophilus parasuis serotype 5 infection by administering a vaccine to a pig, wherein the vaccine contains a protein or an immunogenic fragment thereof as an antigen. Invention also relates to a vaccine, use of a protein having at least 69% sequence identity with a protein according to SEQ ID No: 1, or an immunogenic fragment of said protein, as an antigen for producing a vaccine for protecting a pig from infection with Haemophilus parasuis serotype 4 and infection with Haemophilus parasuis serotype 5, and to a method of protecting a pig from H. parasuis.

EFFECT: invention enables to obtain a vaccine for the preventive treatment of a pig against Haemophilus parasuis infection, which preferably provides protection at least as good as a conventional bacterin vaccine, in particular against the two most common serotypes Haemophilus parasuis, that are serotypes 4 and 5.

9 cl, 3 tbl, 3 ex