THERAPEUTIC USE OF OXIDATIVE HYPOTONIC ACID SOLUTIONS Russian patent published in 2024 - IPC A61K33/20 A61P17/02 A61P31/14 

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions relates to uses of a pharmaceutical composition containing a hypotonic acidic oxidative aqueous solution having pH of 2.5 to 6, a chloride content of less than 400 mg/l and a free chlorine content of 20–140 mg/l, wherein the free chlorine content is more than or equal to 90% hypochlorous acid (HClO), less than or equal to 10% chlorine (Cl₂) and less than or equal to 3% hypochlorite (ClO^-), for local treatment of a wound caused by epidermolysis bullosa (EB), for the local treatment of epidermal growth factor receptor (EGFR) inhibitor-induced dermal toxicity, for the treatment of local disorder caused by Hailey-Hailey disease (HHD), for local treatment of Buruli ulcers caused by mycobacterium ulcerans, for local treatment of SARS-CoV-2 infection.

EFFECT: group of inventions provides the development of a hypotonic acidic oxidative aqueous solution having unexpected versatility in the treatment of several specific localized conditions and respiratory infections, such as epidermolysis bullosa (EB), EGFR inhibitor-induced dermal toxicity, Hailey-Hailey disease (HHD) injuries, Buruli ulcer and SARS-CoV-2 infection.

20 cl, 8 dwg, 9 tbl, 7 ex