PEPTIDE Ac-His-Ala-Glu-Glu-NH AND ITS DERIVATIVES INTENDED FOR RESTORATION OF DEFICIENCY OF ENDOGENOUS COMPONENT OF HUMAN BLOOD Russian patent published in 2024 - IPC A61K38/04 A61K38/07 A61P25/00 A61P25/28 A61P43/00 C07K5/10 C07K5/117 

FIELD: medicine; chemistry.

SUBSTANCE: invention relates to chemistry and medicine, namely to use of peptide Ac-His-Ala-Glu-Glu-NH₂ with N-terminal acetyl group and C-terminal amide group (HAEE) or its pharmaceutically acceptable salts or its pharmaceutically acceptable complexes with metal cations to restore physiologically normal concentration of endogenous HAEE in human blood.

EFFECT: invention provides the possibility of restoring the physiologically normal concentration of endogenous HAEE in the blood in diseases or disorders of human health associated with neuroinflammation and characterized by a drop in the level of endogenous HAEE in blood compared to the norm.

3 cl, 1 dwg, 6 tbl, 4 ex