ANTIBODY-DRUG CONJUGATE TARGETING TROP2, AND METHOD FOR PREPARING AND USING SAME Russian patent published in 2024 - IPC A61K47/68 C07K16/28 A61P35/00 

Abstract RU 2822663 C1

FIELD: biotechnology.

SUBSTANCE: described is a group of inventions comprising an anti-TROP2 antibody-drug conjugate, a method of producing an anti-TROP2 antibody-drug conjugate, a pharmaceutical composition for the treatment and/or prevention of TROP2-positive gastric cancer, use of the conjugate or pharmaceutical composition in the manufacture of a TROP2 protein inhibitor, use of the conjugate or pharmaceutical composition for treating and/or preventing TROP2-positive gastric cancer.

EFFECT: invention extends the range of TROP2 binding agents.

12 cl, 1 dwg, 7 tbl, 5 ex

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RU 2 822 663 C1

Authors

Guo, Qingsong

Shen, Yijun

Yang, Tong

Bao, Bin

Gao, Bei

Wu, Fang

Xu, Jun

Dates

2024-07-11Published

2020-12-18Filed