COMPOSITIONS CONTAINING CURONES AND WAYS OF APPLICATION THEREOF Russian patent published in 2024 - IPC C12N15/86 C12N7/00 C07K14/05 A61P35/00 

FIELD: biotechnology.

SUBSTANCE: described is a group of inventions comprising a synthetic particle for delivering a genetic element into a eukaryotic cell (embodiments), a genetic element for delivering an exogenous effector (embodiments), a pharmaceutical composition for delivering a genetic effector, a host cell for producing a synthetic particle (embodiments), use of a synthetic particle or a pharmaceutical composition for delivering a genetic element to a host cell, use of the synthetic particle or pharmaceutical composition for treating an immune disorder, interferonopathy, an infectious disease, an inflammatory disorder, an autoimmune condition or cancer in a subject, method of treating a disease or disorder in a subject, comprising administering to the subject a synthetic particle or pharmaceutical composition, where the disease or disorder is selected from an immune disorder, an interferonopathy, an inflammatory disorder, an autoimmune condition and cancer, and a method for preparing the composition based on the synthetic particle.

EFFECT: invention extends the range of means for delivering a genetic element into a eukaryotic cell.

46 cl, 22 dwg, 23 tbl, 25 ex