METHOD OF DIFFERENTIATING GENOME OF FOOT-AND-MOUTH DISEASE VIRUS OF INDUSTRIAL STRAINS OF SEROTYPE A BY ANALYZING MAXIMUM MELTING POINTS OF PCR PRODUCTS USING INTERCALATING DYE SYBR GOLD Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6876 

Abstract RU 2823777 C1

FIELD: virology.

SUBSTANCE: described is a method for differentiating the genome of the foot-and-mouth disease virus of industrial strains of serotype A by analyzing maximum melting points of PCR products using the SYBR Gold intercalating dye and specific oligonucleotide primers.

EFFECT: developed method makes it possible to: increase sensitivity and specificity, increase reliability of the analysis, using high-resolution peak analysis to differentiate industrial strains of serotype A foot-and-mouth disease virus.

2 cl, 1 dwg, 6 tbl, 3 ex

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RU 2 823 777 C1

Authors

Doronin Maksim Igorevich

Mikhalishin Dmitrij Valerevich

Borisov Aleksej Valerevich

Okovytaya Tatyana Vladimirovna

Guseva Marina Nikolaevna

Elkina Yuliya Sergeevna

Ruchnova Olga Ivanovna

Dates

2024-07-30Published

2023-08-18Filed