PRESSED NICOTINE LOZENGE Russian patent published in 2024 - IPC A61K31/465 A61K47/26 A61K9/20 A61K9/24 A61P25/34 

FIELD: smoking accessories.

SUBSTANCE: group of inventions relates to a water-soluble pressed lozenge for nicotine cravings relief and a method for production thereof. Water-soluble pressed nicotine lozenge for oral administration comprises a first module and a second module, the first and second modules are connected by crimping, first and second modules are formed by a plurality of compacted particles, the first module is a resorption module containing at least one sugar alcohol in an amount of at least 50 wt.% of first module, and the second module is an FDT module containing at least one sugar alcohol in an amount of at least 50 wt.% of second module, and nicotine, where the second module contains a baking powder, where the second module contains nicotine in amount of 0.2 to 5 wt.% of second module, where the leavening agent contains a superdisintegrant, where the superdisintegrant includes cross-linked polymers, where the amount of superdisintegrant is from 1 to 14 wt.% of second module, where the first module does not contain nicotine and where the first module contains a flavouring agent. Method for production of water-soluble pressed nicotine lozenge for oral administration includes the following stages: providing a first powder composition and a second powder composition, where the first powder composition contains at least one sugar alcohol in an amount of at least 50 wt.% of first powder composition, second powder composition contains at least one sugar alcohol in an amount of at least 50 wt.% of a second powder composition, and nicotine; pressing the first powder composition and the second powder composition to produce a modular lozenge, combined by pressing with the FDT-module, where the second powder composition contains a baking powder, where the second powder composition contains nicotine in amount of 0.2 to 5 wt.% of second powder composition, where baking powder contains superdisintegrant, where the superdisintegrant includes cross-linked polymers, where the amount of superdisintegrant is from 1 to 14 wt.% of second module, where the first module does not contain nicotine and where the first module contains a flavouring agent. Water-soluble pressed nicotine lozenge for oral administration comprises a first module and a second module, the first and second modules are combined by pressing, first and second modules are formed by a plurality of compressed particles, the first module is a modular lozenge and the second module is an FDT module containing nicotine, where the second module contains a baking powder, where the second module contains nicotine in amount of 0.2 to 5 wt.% of second module, where baking powder contains superdisintegrant, where superdisintegrant includes cross-linked polymers, where the amount of superdisintegrant ranges from 1 to 14 wt.% of second module, where the first module does not contain nicotine and where the first module contains a flavouring agent.

EFFECT: above-described compositions effectively relieve craving for nicotine, mask burning sensation.

80 cl, 1 dwg, 13 tbl, 70 ex