FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, in particular to such compositions as aqueous liquid compositions and lyophilized compositions containing recombinant human acid sphingomyelinase. Also disclosed is a method for preparing the lyophilised composition, a bottle for containing the lyophilised composition and an article containing the bottle. There are also provided methods of using the compositions for treating patients with acid sphingomyelinase deficiency.
EFFECT: invention provides effective treatment of patients with acid sphingomyelinase deficiency.
20 cl, 10 dwg, 2 tbl, 2 ex
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