LYOPHILISED DNA COMPOUNDS FOR INCREASED PLASMID DNA EXPRESSION Russian patent published in 2012 - IPC C12N15/63 C07H21/04 A61P9/10 

Abstract RU 2470995 C2

FIELD: medicine.

SUBSTANCE: invention refers to a lyophilised DNA compound to be applied for treating an ischemic disease and to a method of treating an ischemic disease in an individual. The lyophilised DNA compound contains plasmid DNA, salt and carbohydrate wherein said plasmid DNA contains HGF gene, or its version, and wherein said HGF gene, or its version is specified in a group consisting of flHGF, dHGF, NK1, NK2, NK4 or their mixture. The method of treating an ischemic disease in a human or a mammal involves the introduction of a composition recovered from the lyophilised DNA compound by direct injection.

EFFECT: invention enables effective treatment of the ischemic disease in the human or the mammal.

14 cl, 5 dwg, 2 tbl, 5 ex

Similar patents RU2470995C2

Title Year Author Number
TREATMENT OF NEUROPATHY WITH DNA STRUCTURES ENCODING IGF-1 AND DNA STRUCTURES ENCODING HGF 2019
  • Li, Dzhunkhun
  • Li, Naen
  • Ko, Ken, Ryan
RU2781980C2
LYOPHILIZED PHARMACEUTICAL COMPOSITIONS FOR NAKED DNA GENE THERAPY 2019
  • Chan, Beon, Seon
RU2795471C2
ANTI-LILRB1 ANTIBODY AND USES THEREOF 2021
  • Choi, Yoon Aa
  • Kim, Han Byul
  • Kang, Shinyoung
  • Kim, Jung A
  • Kim, Heehang
  • Kim, Minsoon
  • Cho, Junhaeng
RU2813373C1
MODIFIED MITOCHONDRIA AND THEIR USE 2019
  • Han, Kyuboem
  • Kim, Chun-Hyung
  • Kim, Yu Jin
  • Yu, Shin-Hye
  • Kim, Nayoung
  • Kim, Mi Jin
  • Choi, Yong-Soo
  • Lee, Seo Eun
RU2811467C2
COMPOSITION FOR RELIEVING OR TREATING PAIN 2017
  • Kim, Sujeong
  • Choi, Heonsik
  • Kwon, Yejin
  • Kim, Minjung
  • Kim, Minju
  • Kim, Daewook
  • Park, Jangjoon
  • Cho, Jongho
  • Lee, Soondong
  • Kim, Joonsung
  • Sim, Yeomoon
RU2725830C1
ANTI-LILRB1 ANTIBODY AND ITS USE 2020
  • Choi, Yoon Aa
  • Kim, Jung A
  • Jung, Saem
  • Lee, Ji Hyun
  • Na, Kyubong
  • Kim, Yeonchul
  • Kim, Han Byul
RU2801535C1
NEW O-SUCCINYL HOMOSERINE TRANSFERASE VARIANT AND METHOD FOR SYNTHESIS OF O-SUCCINYL HOMOSERINE USING SAID VARIANT 2018
  • Kim Kyungrim
  • Shim Jihyun
  • Kim Hyun Ah
  • Shin Yong Uk
  • Lee Peter
RU2747493C1
NEW O-SUCCINYL HOMOSERINE TRANSFERASE MUTANT AND METHOD FOR SYNTHESIS OF O-SUCCINYL HOMOSERINE USING SAID MUTANT 2018
  • Kim Kyungrim
  • Shim Jihyun
  • Kim Hyun Ah
  • Shin Yong Uk
  • Lee Peter
RU2747494C1
MICROORGANISMS PRODUCING L-VALINE, AND METHOD OF PRODUCING L-VALINE USING SAME 2021
  • Chang Jin Sook
  • Kim Seon Hye
  • Yoon Byoung Hoon
  • Kim Ju-Yeon
  • Kim Hyung Joon
  • Choi Sun Hyoung
RU2822660C1
ANTI-HUMAN ANGIOPOIETIN-LIKE 4 PROTEIN ANTIBODIES 2010
  • Sliman U. Mark
  • Gusarova Viktorija
  • Kim Dzee Kh.
  • Chen Gan
RU2580045C2

RU 2 470 995 C2

Authors

Kim Dzong-Mook

Kim Sudzeong

Khan Voong

Joo Vonsun

Dates

2012-12-27Published

2009-04-09Filed