FIELD: chemistry.
SUBSTANCE: invention relates to antibody-drug conjugates containing a cyclic dinucleotide of formula IIk, which is a STING agonist, conjugated with an antibody, methods for preparing them and using them.
EFFECT: antibody-sting agonist conjugates and their use in immunotherapy are disclosed.
39 cl, 5 dwg, 4 tbl, 7 ex
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Authors
Dates
2024-09-06—Published
2020-07-20—Filed