METHOD FOR DETERMINING RISK OF DEVELOPING AND PROGRESSION OF CHRONIC KIDNEY DISEASE OF VARIABLE AETIOLOGY IN ADULTS Russian patent published in 2024 - IPC A61B5/55 A61B5/26 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to X-ray diagnostics, nephrology, urology, and can be used for determination of risk of development and progression of chronic kidney disease (CKD) of variable aetiology in adults. Magnetic resonance imaging of kidneys in diffusion-weighted images (DWI) mode is performed. ASL-perfusion of renal parenchyma on both sides and measured diffusion coefficient (MDC) are determined. If there is no diffusion limitation, the MDC is from 2.0 to 4.9×10^-3 mm²/s, ASL-perfusion from 390 to 436 ml/100 g/min, indicates a risk of CKD. If there is no restriction of diffusion in the renal parenchyma, the MDC is greater than or equal to 5.1×10^-3 mm²/s, ASL-perfusion from 294 to 402 ml/100 g/min – CKD is diagnosed with no risk of progression. If there are diffusion restrictions, the MDC is from 1.1 to 5.0×10^-3 mm²/sec, ASL-perfusion from 294 to 436 ml/100 g/min – CKD with risk of progression is diagnosed. If there is no diffusion limitation, MDC 1.0×10^-3 mm²/sec, ASL-perfusion more than 437 ml/100 g/min – CKD is absent.

EFFECT: method provides well-timed non-invasive determination of risk of development and progression of CKD of variable aetiology in adults due to MRI in mode of DWI and determination of ASL-perfusion.

1 cl, 10 ex