FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, particularly to a DNA aptamer specific to glial brain tumour cells. Said aptamer has the sequence SEQ ID NO: 1 or SEQ ID NO: 2. Present invention also relates to a conjugate of said DNA aptamer with a fluorescent label, a composition containing said conjugate, as well as a method for intraoperative staining of glial brain tumour cells using such a composition.
EFFECT: invention provides high specificity and affinity of DNA aptamers to glioblastoma cells and high accuracy of determining true boundaries of said tumour during surgery.
16 cl, 11 dwg, 5 ex
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