FABPEG AMPHIPHILIC POLYMERS FOR MODIFYING LIPID MEMBRANE SYSTEMS USED IN BIOLOGY AND MEDICINE, METHOD OF PRODUCING FABPEG AMPHIPHILIC POLYMERS FOR MODIFYING LIPID MEMBRANE SYSTEMS, METHOD FOR MODIFYING PARAMETERS OF LIPID SYSTEMS USING FABPEG AMPHIPHILIC POLYMERS AND METHOD FOR MIXING MULTICOMPONENT LIPID MEMBRANE SYSTEMS Russian patent published in 2024 - IPC C07C231/02 C08G65/08 A61K9/127 C08F6/04 

FIELD: biotechnology.

SUBSTANCE: invention relates to modification of lipid membranes. Disclosed are substances of a number of amphiphilic polymers (FABPEG) for modifying lipid membrane systems, consisting of di-derivatives of (1,20)-eicosen-10-dioic acid with linear amino-polyethylene glycols (aminoPEG) with the number of units of one PEG fragment of more than 40 and weight of more than 2,000 amu; method of producing the disclosed chemical FABPEG compounds and using the disclosed FABPEG chemical compounds for modifying the size of water channels of lipid membrane systems.

EFFECT: obtaining amphiphilic polymers consisting of (1,20)-ecozen-10-dioic acid di-derivatives with linear amino-polyethylene glycols, obtaining characteristics of structural parameters of obtained three-component lipid membrane systems, and demonstrating the suitability of the obtained lipid membrane systems for crystallisation of test membrane proteins.

4 cl, 16 dwg, 4 tbl, 5 ex