FIELD: biotechnology.
SUBSTANCE: invention relates to the recombinant production of the sphingosine-1-phosphate receptor type 5 (Sphingosine-1-phosphate receptor 5, S1P5), and can be used to express the S1P5 receptor. A genetic construct with a nucleotide sequence that is optimized for the expression of the S1P5 receptor has been proposed.
EFFECT: invention provides recombinant expression in a eukaryotic system on the cell surface due to the combination of N-terminal peptide fragments and the position of the partner protein in the third intracellular loop, which also stabilizes the protein and helps the formation of crystalline contacts.
1 cl, 5 dwg
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