FIELD: medicine; pharmaceutics.
SUBSTANCE: group of inventions relates to the treatment of diseases of the central nervous system. Oral pharmaceutical composition for preventing or treating diseases of the central nervous system contains 5–35 wt.% particles of carbamate compound of following formula 2:
[Formula 2]
or a pharmaceutically acceptable salt, solvate or hydrate thereof as an active ingredient; 55–90 wt.% diluent; 2–6 wt.% baking powder; 0.1–4 wt.% sliding substance, where the particle diameter d(0.9) of the active ingredient particles is less than 300 mcm. Also disclosed is a method of producing an oral pharmaceutical composition.
EFFECT: group of inventions provides a stable rate of dissolution of the composition.
13 cl, 1 dwg, 2 tbl, 5 ex
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Authors
Dates
2024-10-30—Published
2020-11-20—Filed