FIELD: chemistry.
SUBSTANCE: invention relates to a trinucleotide capping reagent of formula
,
where R is H or Me, or a salt thereof, suitable for a transcription reaction, as well as to a complex for cotranscriptional capping of mRNA, a method for production thereof and use of a trinucleotide capping reagent for cotranscriptional capping of mRNA.
EFFECT: novel trinucleotide capping reagent is obtained, which is incorporated into the mRNA structure cotranscriptionally and provides improved efficiency of mRNA translation.
5 cl, 3 dwg, 16 ex
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Authors
Dates
2024-10-31—Published
2024-06-18—Filed