FIELD: medicine; pharmaceutics.
SUBSTANCE: invention relates to a mixture of gabapentin and ketoprofen for preventing, relieving or treating pain and/or inflammation. Molar ratio of gabapentin:ketoprofen is 1:1 and wherein said ketoprofen is ketoprofen lysine. Invention also relates to a pharmaceutical composition.
EFFECT: use of the presented invention prolongs the duration of the effect on inflammation and pain and increases the penetration of gabalentin into the brain as compared to taking gabapentin only.
11 cl, 7 dwg, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANALGETIC COMPOSITION AND A METHOD OF ANALGETIC EFFECT ATTAINMENT IN HUMAN | 1993 |
|
RU2125873C1 |
| CO-CRYSTALLINE FORMS OF TRAMADOL AND NSAID | 2009 |
|
RU2599717C2 |
| EMPLOYMENT OF (R)-ARYLPROPIONIC ACIDS TO PREPARE DRUGS FOR TREATMENT OF HUMANS AND ANIMALS LIABLE TO BE THERAPEUTICALLY AFFECTED VIA NF-κB ACTIVATION INHIBITION | 2000 |
|
RU2250103C2 |
| CO-CRYSTALS OF TRAMADOL AND COXIBS | 2010 |
|
RU2547830C2 |
| PHARMACEUTICAL COMPOSITIONS OF COCRYSTALS OF TRAMADOL AND COXIBS | 2011 |
|
RU2567843C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING GABAPENTIN OR ITS ANALOG AND α-AMINOAMIDE AND ITS USING AS ANALGESIC | 2002 |
|
RU2295337C2 |
| PAINLESS INJECTED COMPOSITIONS CONTAINING SALTS OF 2-ARYL PROPIONATE ACIDS | 2003 |
|
RU2340334C2 |
| ANALGESIC COMPOSITIONS | 2019 |
|
RU2820449C2 |
| METHOD OF TREATING NEUROPATHIC PAIN AND ASSOCIATED WITH IT SYNDROMES | 2005 |
|
RU2433825C2 |
| CARBAMATE DERIVATIVES USED FOR PAIN TREATMENT | 2002 |
|
RU2283106C2 |
