FIELD: organic chemistry; pharmacology.
SUBSTANCE: invention relates to use of 4-substituted 3,5-dihydroxy-5-(trichloromethyl)furan-2(5H)-one of formula:
, where Ar=Ph (1); Ar=4-CH3C6H4(2); Ar=3,4-(CH3O)2C6H3 (3); Ar=4-ClC6H4 (4); Ar=4-BrC6H4 (5); Ar=naphth-2-yl (6), as an agent having antimicrobial activity on S. aureus.
EFFECT: antimicrobial activity with respect to Staphylococcus aureus of compounds of formula 1–6.
1 cl, 1 tbl, 8 ex
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