DISCLOSED ARE 4-SUBSTITUTED 3,5-DIHYDROXY-5-(TRICHLOROMETHYL)FURAN-2(5H)-ONES HAVING ANTIMICROBIAL ACTIVITY Russian patent published in 2024 - IPC C07D307/62 A61K31/341 A61P31/04 

Abstract RU 2831255 C2

FIELD: organic chemistry; pharmacology.

SUBSTANCE: invention relates to use of 4-substituted 3,5-dihydroxy-5-(trichloromethyl)furan-2(5H)-one of formula: , where Ar=Ph (1); Ar=4-CH3C6H4(2); Ar=3,4-(CH3O)2C6H3 (3); Ar=4-ClC6H4 (4); Ar=4-BrC6H4 (5); Ar=naphth-2-yl (6), as an agent having antimicrobial activity on S. aureus.

EFFECT: antimicrobial activity with respect to Staphylococcus aureus of compounds of formula 1–6.

1 cl, 1 tbl, 8 ex

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RU 2 831 255 C2

Authors

Lisovenko Natalia Iurevna

Kharitonova Svetlana Sergeevna

Balandina Svetlana Iurevna

Dates

2024-12-03Published

2023-03-16Filed