FIELD: chemistry.
SUBSTANCE: invention relates to novel biologically active compounds of the class of spiro-thiohydantoins namely 8-hydroxy-6-(2-hydroxyphenyl)-9-aroyl-1-(phenylamino)-2-thioxo-1,3,6-triazaspiro[4.4]non-8-ene-4,7-diones of general formula
.
EFFECT: obtaining novel compounds having antimicrobial activity, which can be used in pharmacology as potential drugs with antimicrobial properties.
1 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIALKYL-2-THIOXO-1,3,6-TRIAZASPIRO[4.4 NON-8-ENE-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Tretyakov Nikita Alekseevich
- Balandina Svetlana Yurevna
|
RU2763731C1 |
| THE USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-EN-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY AGAINST S. AUREUS |
2022 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2790379C1 |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-[2-(HYDROXYMETHYL)PHENYL]-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-EN-4,7-DIONE AS AN AGENT HAVING ANTIMICROBIAL ACTIVITY |
2022 |
- Maslivets Anna Andreevna
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
- Muliukova Alina Borisovna
- Andreeva Anastasiia Aleksandrovna
- Poturaev Petr Sergeevich
|
RU2790482C1 |
| (Z)-9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-(((Z)-2-OXOINDOLIN-3-YLIDENE)HYDRAZONO)-1-THIA-3,6-DIAZASPIRO[4.4 ]NON-8-EN-4,7-DIONES WITH ANTIMICROBIAL ACTIVITY |
2021 |
- Mashevskaya Irina Vladimirovna
- Dmitriev Maksim Viktorovich
- Balandina Svetlana Yurevna
- Lukmanova Dzhamilya Nailevna
|
RU2763739C1 |
| METHOD OF PRODUCING 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-3-PHENYL-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-2,4,7-TRIONES HAVING ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Balandina Svetlana Yurevna
- Kobelev Aleksandr Ivanovich
- Babikova Natalya Vladimirovna
|
RU2767558C1 |
| ANTITUBERCULOSIS AGENT BASED ON (Z)-9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-(((E)-PYRIDIN-3-YLMETHYLENE)HYDRAZONO)-1-THIA-3,6-DIAZOSPIRO[4.4]NON-8-ENE-4,7-DIONES |
2023 |
- Lukmanova Dzhamilia Nailevna
- Mashevskaia Irina Vladimirovna
- Balandina Svetlana Iurevna
|
RU2808987C1 |
| USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-4,7-DIONES AS AGENTS WITH ANALGESIC ACTIVITY |
2023 |
- Maslivets Andrei Nikolaevich
- Kobelev Aleksandr Ivanovich
- Makhmudov Ramiz Ragibovich
|
RU2810074C1 |
| METHOD OF PRODUCING 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-1,3-DIPHENYL-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-2,4,7-TRIONES, HAVING ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Balandina Svetlana Yurevna
- Kobelev Aleksandr Ivanovich
- Babikova Natalya Vladimirovna
|
RU2767555C1 |
| ANTIOXIDANT BASED ON 2-[(R-BENZYLIDENE)HYDRAZONO]-8-HYDROXY-6-(2-HYDROXYPHENYL)-9-(4-BROMBENZOYL)-1-THIA-3,6-DIAZASPIRO[4.4]NONA-8-EN-4,7-DIONES |
2023 |
- Lukmanova Dzhamilia Nailevna
- Mashevskaia Irina Vladimirovna
- Dmitriev Maksim Viktorovich
|
RU2806329C1 |
| APPLICATION OF 2-[(R-BENZYLIDENE)HYDRAZONO]-8-HYDROXY-6-(2-HYDROXYPHENYL)-9-AROYL-1-THIA-3,6-DIAZASPIRO[4.4]NONA-8-EN-4,7-DIONES AS AGENTS WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Mashevskaia Irina Vladimirovna
- Lukmanova Dzhamilia Nailevna
- Apushkin Danila Iurevich
- Utushkina Taisiia Andreevna
- Iakushina Karolina Evgenevna
- Andreev Aleksandr Igorevich
|
RU2783241C1 |
